Colts Vs Cardinals Defense 2021. December 25 2021 1239 pm ET. The Indianapolis Colts are set to take on the Arizona Cardinals in a primetime Christmas Day showdown.
There is variance in advanced metrics on all occasions. Colts odds spread line. Cardinals -2 Odds provided by DraftKings Sportsbook Moneyline.
Game time TV schedule and how to watch online.
The Indianapolis Colts are 8-6 and need every win they can get to get into the playoffs. Cardinals -130 Colts 110. There is variance in advanced metrics on all occasions. This was always going to be a weird game with the circumstances that developed late.