Colts Vs Cardinals Betting 2021. Cardinals -25 Point total. Indianapolis Colts NFL Week 16 matchup on December 25 2021.
The Colts are 105 on the money line with 4878 implied odds of winning. The Colts are 8-6 overall straight up SU and 4-2 on the road while the Cardinals have a 10-4 record and 3-3 mark at State Farm Stadium. State Farm Stadium Glendale AZ Date.
Cardinals -4 Opening point total.
A 100 money line bet on the Colts wins 105 if they beat the Cardinals. NFL Handicapping Analysis. Arizona Cardinals Week 16 NFL Betting Analysis. The Colts are 8-6 overall straight up SU and 4-2 on the road while the Cardinals have a 10-4 record and 3-3 mark at State Farm Stadium.